MiR-370-3p regulate TLR4/SLC7A11/GPX4 to alleviate the progression of glucocorticoids-induced osteonecrosis of the femoral head by promoting osteogenesis and suppressing ferroptosis
This study is the first to unveil the regulatory interaction between miRNA and ferroptosis in GC-induced ONFH, providing valuable insights into its pathogenesis and identifying potential therapeutic targets.
Authors
- Lingchi Kong (ORCID: https://orcid.org/0000-0001-6472-5383)
- Rongtai Zuo
- Feng Wang (ORCID: https://orcid.org/0000-0002-4659-0021)
- Shanyu Li
- Qinglin Kang (ORCID: https://orcid.org/0009-0001-9142-6992)
- Bojun Cao (ORCID: https://orcid.org/0000-0001-5769-1699)
- Haojie Shan (ORCID: https://orcid.org/0000-0001-7193-7878)
- Junjie Guan (ORCID: https://orcid.org/0000-0001-5541-7573)
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Sixth People's Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1016/j.jot.2024.10.014
- Citations
- 6
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 5.62