Assessment of Response and Safety of Bulevirtide Treatment in Patients with Chronic Delta Virus Infection: The ARISTOTLE Pilot Observational Study
Bulevirtide effectively reduces HDV RNA levels and improves liver function with a favorable safety profile, offering a promising therapeutic option for chronic hepatitis D. Further large-scale studies are needed to confirm these findings and explore long-term outcomes.
Authors
- Rosa Cotugno
- Paolo Gallo (ORCID: https://orcid.org/0000-0001-8292-1134)
- Luca Rinaldi (ORCID: https://orcid.org/0000-0002-6541-3821)
- Elisabetta Falbo (ORCID: https://orcid.org/0009-0009-0680-3078)
- Nicolina Capoluongo
- F. Benanti
- Francesca Terracciani (ORCID: https://orcid.org/0000-0002-4778-4194)
- Mauro Viganò (ORCID: https://orcid.org/0000-0003-0769-1767)
- Alessandro Loglio (ORCID: https://orcid.org/0000-0001-8022-8803)
- Vincenzo Messina (ORCID: https://orcid.org/0000-0003-1323-5127)
- Umberto Vespasiani‐Gentilucci (ORCID: https://orcid.org/0000-0002-1138-1967)
- Rodolfo Sacco (ORCID: https://orcid.org/0000-0002-9887-7315)
- Alessandro Perrella (ORCID: https://orcid.org/0000-0003-2812-8500)
- Letizia Marinaro (ORCID: https://orcid.org/0000-0002-0896-1469)
- Maurizio Russello
- Alfredo Caturano (ORCID: https://orcid.org/0000-0001-7761-7533)
- Valerio Rosato (ORCID: https://orcid.org/0000-0002-3584-2414)
- Andrea Mormone
- Ferdinando Carlo Sasso (ORCID: https://orcid.org/0000-0002-9142-7848)
- Alessia Ciancio (ORCID: https://orcid.org/0000-0003-4188-0609)
- Carlo Acierno (ORCID: https://orcid.org/0000-0002-1239-7012)
- Emanuela Ciracì (ORCID: https://orcid.org/0000-0001-9942-0766)
- Marco Distefano (ORCID: https://orcid.org/0000-0003-2616-4276)
- Carlo Cosentino (ORCID: https://orcid.org/0000-0001-5599-8187)
- Grazia Anna Niro (ORCID: https://orcid.org/0000-0002-6169-9586)
- Giovanni Villone
- Aldo Marrone (ORCID: https://orcid.org/0000-0001-7329-4159)
- Ernesto Claar (ORCID: https://orcid.org/0000-0002-0819-6023)
- Giulio Petronio Petronio (ORCID: https://orcid.org/0000-0002-5098-7785)
- Antonio Izzi (ORCID: https://orcid.org/0000-0001-6776-5655)
- M.R. Cannavò
- Valeria Pace Palitti
- Giuseppe Cariti
- Chiara Petrucciello
Institutions
- University of Foggia (IT)
- University of Molise (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Casa Sollievo della Sofferenza (IT)
- University of Catania (IT)
- Ospedale San Carlo (IT)
- Ospedale Garibaldi (IT)
- Ospedale Papa Giovanni XXIII (IT)
- Villa Pineta Hospital (IT)
- Campus Bio Medico University Hospital (IT)
- Azienda USL di Pescara (IT)
- Ospedale Sant'Anna (IT)
- Ospedale D. Cotugno (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- BioAge (Italy) (IT)
- University of Turin (IT)
Publication Details
- Journal
- Viruses
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3390/v17020251
- Citations
- 5
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 6.61