External Evaluation of Longitudinal Population Pharmacokinetic Models of Vancomycin in Patients With Osteoarticular Infections

The 2 evaluated models showed poor predictive performance in our local study population. Further studies should explore new strategies to incorporate a longitudinal component and consider other relevant clinical covariates to develop improved longitudinal popPK models for vancomycin.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-02-12
DOI
https://doi.org/10.1097/ftd.0000000000001303
Citations
2
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
2.79
Controls
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article

External Evaluation of Longitudinal Population Pharmacokinetic Models of Vancomycin in Patients With Osteoarticular Infections

Van Dong Nguyen, Amélie Marsot, Aurore Côté
2 citations
Therapeutic Drug Monitoring
Antimicrobial Resistance in Staphylococcus
2.79
article

External Evaluation of Longitudinal Population Pharmacokinetic Models of Vancomycin in Patients With Osteoarticular Infections

Van Dong Nguyen, Amélie Marsot, Aurore Côté
article en
2 citations

Abstract

The 2 evaluated models showed poor predictive performance in our local study population. Further studies should explore new strategies to incorporate a longitudinal component and consider other relevant clinical covariates to develop improved longitudinal popPK models for vancomycin.

Therapeutic Drug MonitoringVol. 47(4)
McGill University Health Centre (CA), Université de Montréal (CA)
Openalex Percentile: Top 13%
Antimicrobial Resistance in Staphylococcus
2.79
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