Ultrastructural changes of skeletal muscle tissue of patients with dysferlinopathy
Despite the non-specificity of the identified ultrastructural alterations, electron microscopy of skeletal muscle biopsies in dysferlinopathy can provide additional information about the mechanisms underlying the disease development. The finding of myosatellite cell and telocyte necrosis indicates the impairment of skeletal muscle regenerative capacity, which may be a novel link in the pathogenesis of dysferlinopathy.
Authors
- С. Н. Бардаков (ORCID: https://orcid.org/0000-0002-3804-6245)
- И. А. Чекмарева (ORCID: https://orcid.org/0000-0003-0126-4473)
- Igor S. Limaev (ORCID: https://orcid.org/0000-0002-0994-9787)
- A.M. Emelin (ORCID: https://orcid.org/0000-0003-4109-0105)
- Roman V. Deev (ORCID: https://orcid.org/0000-0001-8389-3841)
Institutions
- S. M. Kirov Military Medical Academy (RU)
- Research Institute of Human Morphology (RU)
Publication Details
- Journal
- Russian Journal of Archive of Pathology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.17116/patol20258701128
- Citations
- 1
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81