Compartmentalization of High Infratemporal Fossa in Oral Cavity Squamous Cell Carcinomas and Its Impact on Clinical Outcome

Baseline imaging plays a critical role in guiding individualized treatment and predicting clinical outcomes. Low ITF involvement and disease limited to the high retroantral fat compartment exhibit similar clinical outcomes. Among the posterior high ITF compartments, involvement of the pterygopalatine fossa and pterygomaxillary fissure (compartment 3c) is associated with the worst prognosis and poor response to chemotherapy. Subcompartmentalization of ITF involvement provides valuable prognostic information to tailor treatment strategies.

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Publication Details

Journal
Current Oncology
Published
2025-02-10
DOI
https://doi.org/10.3390/curroncol32020099
Citations
3
Primary Topic
Head and Neck Surgical Oncology
Type
article
Field-Weighted Citation Impact
6.02
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article

Compartmentalization of High Infratemporal Fossa in Oral Cavity Squamous Cell Carcinomas and Its Impact on Clinical Outcome

Ujjwal Agarwal, Prathamesh Pai, Swapnil Ulhas Rane, Richa Vaish et al.
3 citations
Current Oncology
Head and Neck Surgical Oncology
6.02
article

Compartmentalization of High Infratemporal Fossa in Oral Cavity Squamous Cell Carcinomas and Its Impact on Clinical Outcome

Ujjwal Agarwal, Prathamesh Pai, Swapnil Ulhas Rane, Richa Vaish, Nandini Menon, Renuka Ashtekar, Nivedita Chakrabarty, Vanita Noronha, Munita Bal, Asawari J. Patil, Abhishek Mahajan, Sarbani Ghosh‐Laskar, Neha Mittal, Pankaj Chaturvedi, Vijay Maruti Patil, Anil K. D’Cruz, Vasundhara Smriti, Kumar Prabhash
article en
3 citations

Abstract

Baseline imaging plays a critical role in guiding individualized treatment and predicting clinical outcomes. Low ITF involvement and disease limited to the high retroantral fat compartment exhibit similar clinical outcomes. Among the posterior high ITF compartments, involvement of the pterygopalatine fossa and pterygomaxillary fissure (compartment 3c) is associated with the worst prognosis and poor response to chemotherapy. Subcompartmentalization of ITF involvement provides valuable prognostic information to tailor treatment strategies.

Current OncologyVol. 32(2)
University of Liverpool (GB), Homi Bhabha National Institute (IN), Tata Memorial Hospital (IN), Clatterbridge Cancer Centre NHS Foundation Trust (GB), Advanced Centre for Treatment, Research and Education in Cancer (IN)
Openalex Percentile: Top 5%
Head and Neck Surgical Oncology
6.02
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