Visceral Leishmaniasis in a 25-Year-Old Female Kidney Transplant Recipient from a Non-Endemic Region: A Case Report from Romania

Visceral leishmaniasis is a rare parasitic infection in non-endemic regions such as Romania. We report the case of a 25-year-old female kidney transplant recipient from Cluj County, Romania, who developed persistent bicytopenia with anemia and thrombocytopenia. Despite no history of travel outside Cluj County and being the only organ recipient from the same donor to experience signs and symptoms, she was diagnosed with visceral leishmaniasis. The second bone marrow aspirate performed revealed <i>Leishmania</i> amastigotes. She was quickly sent to Victor Babes Infectious Disease Hospital in Bucharest for additional tests and treatment. The kidney function of the patient was maintained. This case highlights the importance of considering leishmaniasis in immunosuppressed patients presenting with unexplained cytopenia, even in non-endemic regions. This is the first documented case of visceral leishmaniasis in a kidney transplant recipient in Romania. The present report could serve as a foundation for future educational programs targeted toward informing both healthcare providers and patients about the risks, diagnosis, and management of leishmaniasis in immunosuppressed individuals in non-endemic regions.

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Journal
Microorganisms
Published
2025-02-12
DOI
https://doi.org/10.3390/microorganisms13020403
Primary Topic
Research on Leishmaniasis Studies
Type
article
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article

Visceral Leishmaniasis in a 25-Year-Old Female Kidney Transplant Recipient from a Non-Endemic Region: A Case Report from Romania

Tudor Rareș Olariu, Alin Gabriel Mihu, Mariana Paţiu, Delia Dima et al.
Microorganisms
Research on Leishmaniasis Studies
article

Visceral Leishmaniasis in a 25-Year-Old Female Kidney Transplant Recipient from a Non-Endemic Region: A Case Report from Romania

Tudor Rareș Olariu, Alin Gabriel Mihu, Mariana Paţiu, Delia Dima, Rodica Lighezan, Daniela Adriana Oatis, Cristina Cismaru
article en

Abstract

Visceral leishmaniasis is a rare parasitic infection in non-endemic regions such as Romania. We report the case of a 25-year-old female kidney transplant recipient from Cluj County, Romania, who developed persistent bicytopenia with anemia and thrombocytopenia. Despite no history of travel outside Cluj County and being the only organ recipient from the same donor to experience signs and symptoms, she was diagnosed with visceral leishmaniasis. The second bone marrow aspirate performed revealed <i>Leishmania</i> amastigotes. She was quickly sent to Victor Babes Infectious Disease Hospital in Bucharest for additional tests and treatment. The kidney function of the patient was maintained. This case highlights the importance of considering leishmaniasis in immunosuppressed patients presenting with unexplained cytopenia, even in non-endemic regions. This is the first documented case of visceral leishmaniasis in a kidney transplant recipient in Romania. The present report could serve as a foundation for future educational programs targeted toward informing both healthcare providers and patients about the risks, diagnosis, and management of leishmaniasis in immunosuppressed individuals in non-endemic regions.

MicroorganismsVol. 13(2)
Iuliu Hațieganu University of Medicine and Pharmacy (RO), Clinical Emergency Hospital Bucharest (RO), Victor Babeș University of Medicine and Pharmacy Timișoara (RO), Institute of Oncology Prof. Dr. Ion Chiricuta (RO), Vasile Goldis Western University of Arad (RO)
Good health and well-being
Openalex Percentile: Top 96%
Research on Leishmaniasis Studies
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Visceral Leishmaniasis in a 25-Year-Old Female Kidney Transplant Recipient from a Non-Endemic Region: A Case Report from Romania — Tudor Rareș Olariu, Alin Gabriel Mihu, et al. · Microorganisms (2025) | TGRS Research Map | TGRS