Dynamic Assessment of Local Abdominal Tissue Concentrations of Cisplatin During a HIPEC Procedure: Insights from a Porcine Model
Our investigation revealed comparable cisplatin concentrations across abdominal organ surfaces, except higher concentrations in the peritoneal lining of the abdominal wall than in the stomach, rectum, and liver. This model holds promise for future research into HIPEC interventions and anticancer effectiveness.
Authors
- Mats Bue (ORCID: https://orcid.org/0000-0001-7215-8323)
- Pelle Hanberg (ORCID: https://orcid.org/0000-0002-6845-1874)
- Elisabeth Krogsgaard Petersen (ORCID: https://orcid.org/0000-0002-5164-5197)
- Andrea René Jørgensen (ORCID: https://orcid.org/0000-0001-6334-3164)
- Bo Martin Bibby (ORCID: https://orcid.org/0000-0002-4742-4076)
- Anne Schmedes (ORCID: https://orcid.org/0000-0002-6305-8563)
- Christina Harlev (ORCID: https://orcid.org/0000-0001-7255-9557)
- Maiken Stilling (ORCID: https://orcid.org/0000-0002-4530-2075)
- Lone Kjeld Petersen (ORCID: https://orcid.org/0000-0002-1424-6170)
Institutions
- University of Southern Denmark (DK)
- Aarhus University (DK)
- Odense University Hospital (DK)
- Aarhus University Hospital (DK)
- Sygehus Sønderjylland (DK)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1245/s10434-025-17000-w
- Citations
- 3
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- Aarhus Universitet
- Kræftens Bekæmpelse
- Riisfort Fonden
- Familien Hede Nielsens Fond
- Fabrikant Einar Willumsens Mindelegat
- Knud og Edith Eriksens Mindefond
- Fonden til Lægevidenskabens Fremme