Role of Mig-6 in adipose tissue: Implications for glucose metabolism and insulin resistance

Adipose-specific overexpression of Mig-6 improves systemic glucose tolerance and insulin sensitivity, suggesting its potential as a target for both the treatment and prevention of diabetes. These findings provide a reference for further research targeting EGFR or Mig-6 in adipose tissue, highlighting the metabolic role of Mig-6 in glucose homeostasis.

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Publication Details

Journal
PLoS ONE
Published
2025-02-12
DOI
https://doi.org/10.1371/journal.pone.0314289
Primary Topic
Adipokines, Inflammation, and Metabolic Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Role of Mig-6 in adipose tissue: Implications for glucose metabolism and insulin resistance

Kyoung Hye Joung, Ok Soon Kim, Ji Min Kim, Sorim Choung et al.
PLoS ONE
Adipokines, Inflammation, and Metabolic Diseases
article

Role of Mig-6 in adipose tissue: Implications for glucose metabolism and insulin resistance

Kyoung Hye Joung, Ok Soon Kim, Ji Min Kim, Sorim Choung, Bon Jeong Ku, Hyun Jin Kim, Ju Hee Lee, Joung Youl Lim
article en

Abstract

Adipose-specific overexpression of Mig-6 improves systemic glucose tolerance and insulin sensitivity, suggesting its potential as a target for both the treatment and prevention of diabetes. These findings provide a reference for further research targeting EGFR or Mig-6 in adipose tissue, highlighting the metabolic role of Mig-6 in glucose homeostasis.

PLoS ONEVol. 20(2)
Chungnam National University (KR)
Good health and well-being
Openalex Percentile: Top 96%
Adipokines, Inflammation, and Metabolic Diseases
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