Resveratrol modulates phosphorylation of ERK and AKT in murine cementoblasts during in vitro orthodontic compression
This study shows a regulation of pAKT and pERK by resveratrol in OCCM-30 cells without a negative effect on cell viability. Therefore, resveratrol may have the potential to modulate the periodontal response to mechanical stimulation.
Authors
- Franziska Coenen
- Sihem Brenji
- Michael Wolf (ORCID: https://orcid.org/0000-0002-5882-3080)
- Marta Rizk (ORCID: https://orcid.org/0000-0002-0093-8934)
- Rogerio Bastos Craveiro (ORCID: https://orcid.org/0000-0003-0768-935X)
- Leon J. Schurgers (ORCID: https://orcid.org/0000-0001-7867-6957)
- Rebekka K. Schneider (ORCID: https://orcid.org/0000-0002-0749-1565)
- Isabel Knaup (ORCID: https://orcid.org/0000-0001-8331-9153)
- Joachim Jankowski (ORCID: https://orcid.org/0000-0002-4528-2967)
- Christian Niederau
- Shams Negm
Institutions
- Maastricht University (NL)
- RWTH Aachen University (DE)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1186/s12903-025-05591-5
- Citations
- 2
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 2.45
Funders
- Deutsche Forschungsgemeinschaft
- RWTH Aachen University
- National Institutes of Health