CD147-expressed small extracellular vesicles enhance the detection of colorectal neoplasia with fecal immunochemical test
CD147 is superior to FIT for detecting AA and proximal neoplasia. Moreover, CD147 can increase the sensitivity of FIT for detecting either AA or CRC by combinatory use. However, false positivity is the concern of CD147, which should be further resolved in the future.
Authors
- Takahiro Ochiya (ORCID: https://orcid.org/0000-0002-0776-9918)
- Tang‐Long Shen (ORCID: https://orcid.org/0000-0001-6264-3608)
- Li‐Chun Chang (ORCID: https://orcid.org/0000-0001-5325-3974)
- Been‐Ren Lin (ORCID: https://orcid.org/0000-0001-8354-1758)
- Ming‐Shiang Wu (ORCID: https://orcid.org/0000-0002-1940-6428)
- Han‐Mo Chiu (ORCID: https://orcid.org/0000-0003-2786-8056)
Institutions
- Tokyo Medical University (JP)
- National Taiwan University (TW)
- Development Center for Biotechnology (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- ESMO Gastrointestinal Oncology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1016/j.esmogo.2025.100140
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Ministry of Science and Technology, Taiwan