Cannabis use, oral dysbiosis, and neurological disorders
Cannabis (marijuana) is a leafy plant that has medical, recreational, and other uses. Cannabis is socially accepted and widely used throughout the United States. Though cannabis use is increasingly gaining popularity, studies detail the deleterious effects of chronic cannabis smoking on mental health, as well as the immunosuppressive properties of cannabinoids. Additionally, oral dysbiosis induced by cannabis smoking serves as a novel catalyst for neurological abnormalities, potentially possible through microbial translocation via the oral-brain axis. This review summarizes the effects and link of smoking cannabis on neurological abnormalities, immunity, and oral microbiome.
Authors
- Sylvia Fitting (ORCID: https://orcid.org/0000-0002-8906-3133)
- Tabinda Salman (ORCID: https://orcid.org/0000-0002-2866-703X)
- Xiaoyu Fu (ORCID: https://orcid.org/0000-0003-4467-2418)
- Andrew P. Keegan (ORCID: https://orcid.org/0000-0003-1951-7993)
- Wei Jiang (ORCID: https://orcid.org/0000-0002-1374-053X)
- Andreana M. Benitez (ORCID: https://orcid.org/0000-0002-8294-7809)
- Marice McCrorey
- Zhenwu Luo
- Douglas E. Johnson
- Amber A. Hazzard
Institutions
- University of North Carolina at Chapel Hill (US)
Publication Details
- Journal
- UNC Libraries
- Published
- 2025-02-12
- DOI
- https://doi.org/10.17615/ahgd-1n03
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- Clinical Science Research and Development
- National Institute of General Medical Sciences