Ferric Ammonium Citrate Reduces Claudin-5 Abundance and Function in Primary Mouse Brain Endothelial Cells
Iron overload modulates BBB transporters and junction proteins in vitro, highlighting potential implications for CNS drug delivery in neurodegenerative diseases.
Authors
- Celeste Mawal (ORCID: https://orcid.org/0000-0002-2858-5923)
- Jae Pyun (ORCID: https://orcid.org/0000-0001-7187-6796)
- Ashley I. Bush (ORCID: https://orcid.org/0000-0001-8259-9069)
- Liam M. Koehn (ORCID: https://orcid.org/0000-0003-3845-2953)
- Stephanie A. Newman
- Joseph A. Nicolazzo (ORCID: https://orcid.org/0000-0002-0983-7152)
- Pranav Runwal
Institutions
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1007/s11095-025-03826-2
- Citations
- 2
- Primary Topic
- Barrier Structure and Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- Monash University