Can patient self-evaluation of functional status be used for evaluation of impairment of motor function in Guillain-Barré syndrome? Mapping clinician- and patient-reported outcomes in a phase 3 study of eculizumab in Japan
This study established thresholds for the R-ODS total centile score that could approximate classification of functional impairment in GBS based on the HFGS score. Given that the R-ODS reflects the patient perspective, it may be used to capture a more complete picture of GBS severity.
Authors
- Stéphane Quéré (ORCID: https://orcid.org/0000-0001-8832-6053)
- Angély Loubert (ORCID: https://orcid.org/0000-0002-7588-431X)
- Qun Lin (ORCID: https://orcid.org/0000-0002-9629-5733)
- Antoine Regnault (ORCID: https://orcid.org/0000-0001-8234-2896)
- Hélène Chevrou‐Séverac
- Hirokazu Ishida
- Glen Frick
- Yuko Abeta
Institutions
- Alexion Pharmaceuticals (United States) (US)
- AstraZeneca (Switzerland) (CH)
- AstraZeneca (United States) (US)
- Alexion Pharma (Switzerland) (CH)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3389/fneur.2025.1463938
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AstraZeneca
- Alexion Pharmaceuticals