Exploring the association between BIN1 gene polymorphisms and hippocampal subfield volume in community mild cognitive impairment
This study presents novel findings indicating an association between the <i>BIN1</i> rs10200967 genotype and lHATA atrophy, with the rs10200967 CC genotype showing a higher volume of lHATA in individuals with MCI. These results suggest that the rs10200967 CC genotype may confer a protective effect against MCI, offering a potential basis for early detection and prevention of AD.
Authors
- Chung Yin Kong (ORCID: https://orcid.org/0000-0001-6431-7830)
- Zhenkun Tan (ORCID: https://orcid.org/0000-0001-8973-8949)
- Xinxia Liu (ORCID: https://orcid.org/0009-0008-7516-1462)
- Junjiao Ping (ORCID: https://orcid.org/0009-0001-6454-9444)
- Jiali Luo
- Ying Zhang (ORCID: https://orcid.org/0000-0002-5414-6617)
- Haibo Zhang (ORCID: https://orcid.org/0000-0002-3752-0806)
Institutions
- Zhongshan People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.3389/fneur.2025.1525664
- Citations
- 2
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.33