Serum Exosomal miR-216a Contributes to Acute Pancreatitis-Associated Acute Lung Injury by Enhancing Endothelial Cell Vascular Permeability Through Downregulating LAMC1
In summary, serum exosomal miR-216a can promote the onset and progression of AP-ALI by augmenting endothelial cell vascular permeability. This finding presents a theoretical basis for exploring new therapeutic approaches targeting AP-ALI.
Authors
- Xiangyu Kong (ORCID: https://orcid.org/0000-0001-7515-2613)
- Xianzhu Zhou (ORCID: https://orcid.org/0000-0002-8861-8563)
- Chunting Fu
- Xiaoyang Dong
- Xiaoju Su
- Ge Li (ORCID: https://orcid.org/0000-0003-2907-6503)
- Huiyun Zhu (ORCID: https://orcid.org/0000-0003-4580-8700)
- Yiqi Du (ORCID: https://orcid.org/0000-0002-4261-6888)
- Sun Xing-cheng
Institutions
- Second Military Medical University (CN)
- Changhai Hospital (CN)
- University Gastroenterology (US)
Publication Details
- Journal
- Pancreas
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1097/mpa.0000000000002467
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42