Development of Mucoadhesive Vaginal Films for Metronidazole Delivery Using Methacryloylated, Crotonoylated, and Itaconoylated Gelatin Blends with Poly(vinyl alcohol)
These findings suggest that modified gelatins could serve as effective excipients in designing mucoadhesive formulations for vaginal administration, with potential applications extending to other transmucosal drug delivery systems.
Authors
- Elvira O. Shatabayeva (ORCID: https://orcid.org/0000-0001-9153-5198)
- Zarina A. Kenessova (ORCID: https://orcid.org/0000-0003-2768-824X)
- Vitaliy V. Khutoryanskiy
- Sarkyt E. Kudaibergenov (ORCID: https://orcid.org/0000-0002-1166-7826)
- Daulet B. Kaldybekov (ORCID: https://orcid.org/0000-0002-7191-5465)
- Rysgul N. Tuleyeva (ORCID: https://orcid.org/0000-0002-9691-4274)
Institutions
- Al-Farabi Kazakh National University (KZ)
- Institute of Polymer Materials and Technologies (KZ)
- University of Reading (GB)
Publication Details
- Journal
- AAPS PharmSciTech
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1208/s12249-025-03055-1
- Citations
- 5
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 3.95