Innovative technologies of the application of the immune complex vaccine “Nextmune®” in the prevention of Gambaro’s disease in poultry farming of the meat direction

Infectious bursal disease (IBD) virus is one of the most persistent and prevalent viruses in poultry worldwide, and vaccination alone is the main means of controlling this disease. However, the susceptibility of highly attenuated IBDV vaccine strains to neutralization by maternal antibodies (MDA) and the predominant virulence of partially attenuated strains limit the use of conventional live IBDV vaccines in pre- and post-hatching chickens. Although the disease has been well controlled by the widespread use of commercial vaccines, a new variant strain of IBDV has emerged as a result of strong immunized selection in the field, creating new threats to poultry production. In terms of productivity and economic impact established that Gamboro disease can lead to reduced weight gain, as well as increased feed conversion, secondary infections, slaughterhouse condemnations, mortality and morbidity, resulting in losses and reduced profitability. The article examines the results of serological control of the effectiveness of vaccination of broilers against infectious bursal disease (IBD) using the immunocomplex vaccine Sevak Transmun in the incubator. Immunocomplex vaccines are modern representatives of the evolution of biotechnology, which do not cause post-vaccination complications in birds and do not have interference phenomena. They provide individual immunity formation even with different levels of maternal antibodies (MAT) when administered subcutaneously to day-old chicks or by the in ovo method to 18-day-old chicken embryos. Vaccination in the hatchery with such vaccines is more accurate and provides protection to the whole bird, unlike live vaccines, which are usually administered through drinking water.

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Journal
Scientific Messenger of LNU of Veterinary Medicine and Biotechnology
Published
2024-12-29
DOI
https://doi.org/10.32718/nvlvet11623
Primary Topic
Yersinia bacterium, plague, ectoparasites research
Type
article
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article

Innovative technologies of the application of the immune complex vaccine “Nextmune®” in the prevention of Gambaro’s disease in poultry farming of the meat direction

А. В. Колечко, V. V. Marchenko
Scientific Messenger of LNU of Veterinary Medicine and Biotechnology
Yersinia bacterium, plague, ectoparasites research
article

Innovative technologies of the application of the immune complex vaccine “Nextmune®” in the prevention of Gambaro’s disease in poultry farming of the meat direction

А. В. Колечко, V. V. Marchenko
article en

Abstract

Infectious bursal disease (IBD) virus is one of the most persistent and prevalent viruses in poultry worldwide, and vaccination alone is the main means of controlling this disease. However, the susceptibility of highly attenuated IBDV vaccine strains to neutralization by maternal antibodies (MDA) and the predominant virulence of partially attenuated strains limit the use of conventional live IBDV vaccines in pre- and post-hatching chickens. Although the disease has been well controlled by the widespread use of commercial vaccines, a new variant strain of IBDV has emerged as a result of strong immunized selection in the field, creating new threats to poultry production. In terms of productivity and economic impact established that Gamboro disease can lead to reduced weight gain, as well as increased feed conversion, secondary infections, slaughterhouse condemnations, mortality and morbidity, resulting in losses and reduced profitability. The article examines the results of serological control of the effectiveness of vaccination of broilers against infectious bursal disease (IBD) using the immunocomplex vaccine Sevak Transmun in the incubator. Immunocomplex vaccines are modern representatives of the evolution of biotechnology, which do not cause post-vaccination complications in birds and do not have interference phenomena. They provide individual immunity formation even with different levels of maternal antibodies (MAT) when administered subcutaneously to day-old chicks or by the in ovo method to 18-day-old chicken embryos. Vaccination in the hatchery with such vaccines is more accurate and provides protection to the whole bird, unlike live vaccines, which are usually administered through drinking water.

Scientific Messenger of LNU of Veterinary Medicine and BiotechnologyVol. 26(116)
Vinnytsia National Agrarian University (UA)
Openalex Percentile: Top 72%
Yersinia bacterium, plague, ectoparasites research
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Innovative technologies of the application of the immune complex vaccine “Nextmune®” in the prevention of Gambaro’s disease in poultry farming of the meat direction — А. В. Колечко, V. V. Marchenko · Scientific Messenger of LNU of Veterinary Medicine and Biotechnology (2024) | TGRS Research Map | TGRS