CLIC1 Supports Mechanisms Related to Platelet Activation and Thrombosis
CLIC1 is regulated by adhesive interactions with integrin ligands that cause CLIC1 to relocate to the cell membrane of endothelial cells and platelets. This process in turn appears to be relevant for integrin-mediated functions involved in platelet thrombus formation in vitro and in vivo.
Authors
- Emmanuel Ampofo
- Anna Drawz
- Lynn M. Knowles (ORCID: https://orcid.org/0000-0002-6250-9289)
- Hermann Eichler (ORCID: https://orcid.org/0000-0002-1372-0619)
- Ján Pilch (ORCID: https://orcid.org/0000-0002-2682-4708)
- Michael D. Menger
Institutions
- Saarland University (DE)
Publication Details
- Journal
- Transfusion Medicine and Hemotherapy
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1159/000544115
- Citations
- 1
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- Universität des Saarlandes