NCCN Guidelines® Insights: Head and Neck Cancers, Version 2.2025
The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity (including mucosal lip), pharynx, larynx, and paranasal sinuses, as well as occult primary cancer, salivary gland cancer, and mucosal melanoma (MM). The specific site of disease, stage, and pathologic findings guide treatment (eg, the appropriate surgical procedure, radiation targets, dose and fractionation of radiation, indications for systemic therapy). The NCCN Head and Neck Cancers Panel meets at least annually to review comments from reviewers within their institutions, examine relevant new data from publications and abstracts, and reevaluate and update their recommendations. These NCCN Guidelines Insights summarize the panel's most recent recommendations regarding management of nasopharynx cancer and ongoing research in this area.
Authors
- Bharat B. Mittal (ORCID: https://orcid.org/0000-0002-6541-8753)
- David A. Schwartz (ORCID: https://orcid.org/0000-0002-7026-7099)
- David G. Pfister (ORCID: https://orcid.org/0000-0002-2109-3221)
- David J. Sher (ORCID: https://orcid.org/0000-0003-3943-7480)
- Sharon A. Spencer
- Ellie Maghami
- Debra S. Leizman
- James William Rocco (ORCID: https://orcid.org/0000-0001-5312-0303)
- Christine M. Glastonbury (ORCID: https://orcid.org/0000-0002-9611-1287)
- Maie A. St. John (ORCID: https://orcid.org/0000-0001-7068-9534)
- Francis P. Worden (ORCID: https://orcid.org/0000-0002-6632-4951)
- Jatin P. Shah (ORCID: https://orcid.org/0000-0002-6444-6592)
- Susan Darlow
- Katharine A. Price (ORCID: https://orcid.org/0000-0002-5738-1866)
- Ying J. Hitchcock (ORCID: https://orcid.org/0000-0002-2151-6597)
- Justine Y. Bruce (ORCID: https://orcid.org/0000-0002-5902-7430)
- Loren K. Mell
- Anthony J. Cmelak (ORCID: https://orcid.org/0000-0002-8650-313X)
- David M. Brizel (ORCID: https://orcid.org/0000-0001-9828-4790)
- Andrew C. Birkeland (ORCID: https://orcid.org/0000-0003-2500-2857)
- Paul M. Busse
- Jimmy J. Caudell (ORCID: https://orcid.org/0000-0001-6417-2483)
- Sarah Montgomery (ORCID: https://orcid.org/0000-0002-4189-5416)
- Carole Fakhry (ORCID: https://orcid.org/0000-0002-5251-6178)
- A. Dimitrios Colevas (ORCID: https://orcid.org/0000-0003-3849-4264)
- Michael Kase (ORCID: https://orcid.org/0000-0002-9294-8880)
- Greg Andrew Durm (ORCID: https://orcid.org/0000-0003-2606-745X)
- Wesley L. Hicks (ORCID: https://orcid.org/0000-0003-2916-5231)
- Maura L. Gillison (ORCID: https://orcid.org/0000-0002-8145-5749)
- J.L. Geiger (ORCID: https://orcid.org/0000-0003-4494-9843)
- Robert I. Haddad (ORCID: https://orcid.org/0000-0003-1413-0079)
- Thomas J. Galloway (ORCID: https://orcid.org/0000-0002-5730-2099)
- Sue S. Yom (ORCID: https://orcid.org/0000-0002-0779-7476)
- He Wang (ORCID: https://orcid.org/0000-0002-4904-531X)
- Cristina P. Rodriguez (ORCID: https://orcid.org/0000-0003-3568-2630)
- Antonio Jimeno
- Douglas Adkins
- Gregory Steven Weinstein
- Weining Zhen
- Aditya Juloori (ORCID: https://orcid.org/0000-0002-7486-6208)
- Harlan A. Pinto
Institutions
- Fox Chase Cancer Center (US)
- Roswell Park Comprehensive Cancer Center (US)
- Barnes-Jewish Hospital (US)
- City Of Hope National Medical Center (US)
- Cleveland Clinic (US)
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Tennessee Health Science Center (US)
- Breast Cancer Research Foundation (US)
- University of Utah (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- UC San Diego Health System (US)
- Huntsman Cancer Institute (US)
- Cancer Institute (WIA) (IN)
- Susan Thompson Buffett Foundation (US)
- WinnMed (US)
- Yale Cancer Center (US)
- Moffitt Cancer Center (US)
- Massachusetts General Hospital (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Jewish Hospital (US)
- University of Wisconsin Carbone Cancer Center (US)
- Sidney Kimmel Cancer Center (US)
- University Hospitals Seidman Cancer Center (US)
- Duke Medical Center (US)
- University of Colorado Cancer Center (US)
- Dana-Farber Brigham Cancer Center (US)
- Smilow Cancer Hospital (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Moores Cancer Center
- University of Chicago Medicine Comprehensive Cancer Center
- UCLA Jonsson Comprehensive Cancer Center
- Vanderbilt-Ingram Cancer Center
- Stanford Cancer Institute
- Duke Cancer Institute
- Fred and Pamela Buffett Cancer Center
- UC Davis Comprehensive Cancer Center
- Harold C. Simmons Comprehensive Cancer Center
- O'Neal Comprehensive Cancer Center
- National Comprehensive Cancer Network
- Indiana University (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2025-02-01
- DOI
- https://doi.org/10.6004/jnccn.2025.0007
- Citations
- 98
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 181.10