Successful Unconventional Treatment of Serratia Marcescens Exit-Site Infection in a Central Venous Catheter for Hemodialysis: A Case Report.

<b>Introduction.</b> Central Catheter-related infections and biofilm formation are significant issues in the context of nosocomial infections that increase resistance to conventional therapies. <b>Methodology.</b> This case report describes an unconventional treatment for a Serratia Marcescens Central Venous Catheter infection in a hemodialysis patient through the combination of polyguanide and betaine. Clinical evaluations were conducted using the Visual Exit-Site Score and culture swabs. <b>Results.</b> After the first four treatment sessions there was a significant reduction in redness and pain (VES=1); the culture swab at the end of treatment was negative. <b>Conclusions.</b> The results of this case report encourage further research on the effectiveness of non-antibiotic treatments.