Predictors for regression and progression of actively surveilled cervical intraepithelial neoplasia grade 2: A prospective cohort study
The majority of CIN2 lesions regress in young women. Women with large lesions and/or high-grade referral cytology should perhaps more often be treated instead of active surveillance. Initial hrHPV genotype does not appear to predict outcomes while not harboring hrHPV favors regression.
Authors
- Ralf Bützow (ORCID: https://orcid.org/0000-0003-4366-5099)
- Joakim Dillner (ORCID: https://orcid.org/0000-0001-8588-6506)
- Maija Jakobsson (ORCID: https://orcid.org/0000-0003-0075-8375)
- Karolina Louvanto (ORCID: https://orcid.org/0000-0002-1172-363X)
- Ilkka Kalliala (ORCID: https://orcid.org/0000-0002-7664-0587)
- Anni Virtanen (ORCID: https://orcid.org/0000-0002-7467-8434)
- Laura Bergqvist
- Karoliina Aro (ORCID: https://orcid.org/0000-0003-3467-7194)
- Annu Heinonen (ORCID: https://orcid.org/0000-0001-6424-5857)
- Pekka Nieminen
Institutions
- University of Helsinki (FI)
- Tampere University (FI)
- Helsinki University Hospital (FI)
- Karolinska Institutet (SE)
- Tampere University Hospital (FI)
- Hyvinkää Hospital (FI)
- Tampere University (FI)
- Hospital District of Helsinki and Uusimaa (FI)
- Imperial College London (GB)
Publication Details
- Journal
- Acta Obstetricia Et Gynecologica Scandinavica
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1111/aogs.15032
- Citations
- 5
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- Finska Läkaresällskapet
- Academy of Finland
- Suomalainen Lääkäriseura Duodecim