Plasma Soluble Progenitor Cell Receptors as Biomarkers for Severe Anemia Among Malaria‐Infected Pediatrics: A Prospective Study in Ghana
<i>P. falciparum</i>-infected children had higher plasma levels of sGM-CSFR, sEPO-R and EPO. Plasma sEPO-R correlated negatively with erythrocyte parameters, suggesting a possible contribution of the endogenous receptor to the development of severe anemia in children with malaria. Further studies to investigate the neutralizing effects of sEPO-R on erythropoietic response during malaria are recommended.
Authors
- Gabriel Abbam (ORCID: https://orcid.org/0000-0002-0408-6126)
- Yeduah Quansah (ORCID: https://orcid.org/0000-0001-6320-6952)
- Kofi Mensah (ORCID: https://orcid.org/0000-0002-2238-2797)
- James Edward Mensah (ORCID: https://orcid.org/0000-0003-4133-1722)
- Samuel Yaw Aboagye (ORCID: https://orcid.org/0000-0001-7702-982X)
- Victor Udoh Usanga (ORCID: https://orcid.org/0000-0001-6185-1683)
- Ejike Felix Chukwurah (ORCID: https://orcid.org/0000-0001-5485-3453)
- Samira Daud (ORCID: https://orcid.org/0000-0003-0133-1760)
- Boniface Nwofoke Ukwah (ORCID: https://orcid.org/0000-0002-5203-4056)
- Simon Bannison Bani (ORCID: https://orcid.org/0000-0002-6713-6653)
- Charles A. Derigubah (ORCID: https://orcid.org/0000-0003-1519-3530)
- Peter Kuugemah Selleh (ORCID: https://orcid.org/0009-0000-6309-5236)
- Charles Nkansah (ORCID: https://orcid.org/0000-0001-6986-9976)
- Moses Banyeh (ORCID: https://orcid.org/0000-0003-3594-6077)
- Enoch Boadi
- Felix Osei‐Boakye (ORCID: https://orcid.org/0000-0001-5126-7424)
- Muniru Mohammed Tanko (ORCID: https://orcid.org/0000-0002-0487-8465)
- Samuel Kwasi Appiah (ORCID: https://orcid.org/0000-0003-1855-5840)
- Emmanuel Appiah‐Kubi (ORCID: https://orcid.org/0009-0009-6589-4184)
- Isaac Adjei (ORCID: https://orcid.org/0009-0001-5907-224X)
- Ruby Tater
- Anne Natornaa
- Gilbert Amankwaa
- Onwuka K. Chima
- Sylvanus M. Kpangkpari
- Prince Ottah
Institutions
- Tamale Teaching Hospital (GH)
- Sunyani Technical University (GH)
- Bolgatanga Technical University
- University for Development Studies (GH)
- Ebonyi State University (NG)
Publication Details
- Journal
- Health Science Reports
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/hsr2.70460
- Primary Topic
- Erythropoietin and Anemia Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00