Evaluation of pharmacokinetic and pharmacodynamic similarity of an IDegAsp biosimilar versus the originator in healthy Chinese volunteers
This study demonstrated the PK/PD similarity of 22011 to Ryzodeg with a comparable safety profile.<b>Trial Registration:</b> http://www.chinadrugtrials.org.cn/index.html with an identifier of CTR20230678, registered 15 March 2023.
Authors
- Yerong Yu (ORCID: https://orcid.org/0000-0003-0103-0087)
- Linfeng Guo (ORCID: https://orcid.org/0009-0005-4487-1224)
- Yulei Zhuang (ORCID: https://orcid.org/0009-0005-7322-881X)
- Li Deng (ORCID: https://orcid.org/0009-0004-5690-2078)
- Yang Xiong (ORCID: https://orcid.org/0009-0007-8520-3622)
- Hongling Yu
- Lan Li (ORCID: https://orcid.org/0000-0002-4635-6331)
- Hui Liu (ORCID: https://orcid.org/0000-0002-9599-6853)
- Wenjia Wang (ORCID: https://orcid.org/0000-0003-0336-9412)
- Xinlei Chen (ORCID: https://orcid.org/0000-0003-3570-588X)
- Kanghua Huang (ORCID: https://orcid.org/0009-0004-7981-488X)
- Wengang He
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sunshine Hospital (AU)
Publication Details
- Journal
- Expert Opinion on Investigational Drugs
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1080/13543784.2025.2463085
- Primary Topic
- Biosimilars and Bioanalytical Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00