Wunderlich Syndrome Caused by Spontaneous Rupture of Renal Angiomyolipoma in the Third Trimester of Pregnancy: Endovascular Management With Fetal Preservation—A Case Report and Literature Review

Renal angiomyolipoma (AML) are benign tumors incidentally diagnosed during routine radiologic images; nonetheless, AML rupture is uncommon and has been associated with fatal consequences, demanding prompt intervention, especially during pregnancy with symptoms of Wunderlich's syndrome (WS) and atrophied contralateral kidney. We report a 30-year-old pregnant woman who presented with gross hematuria and hypovolemic shock in her seventh month of pregnancy. Magnetic resonance imaging revealed a 15 × 13.5 × 16 cm AML mass in the left kidney, a 5 × 6 cm intrarenal pseudoaneurysm, and a massive retroperitoneal hematoma with an atrophied contralateral right kidney. After achieving hemodynamic stability, selective renal arterial embolization was performed with a successful outcome. She subsequently delivered her baby via cesarean section without complications. In conclusion, although WS due to AML rupture is rare during pregnancy, accurate diagnosis and prompt endovascular treatment should be pursued in cases involving a solitary kidney and associated comorbid conditions to safeguard the lives of both the patient and the baby, stabilize renal function, and prevent catastrophic complications.

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Publication Details

Journal
Clinical Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1002/ccr3.70183
Primary Topic
Tuberous Sclerosis Complex Research
Type
article
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article

Wunderlich Syndrome Caused by Spontaneous Rupture of Renal Angiomyolipoma in the Third Trimester of Pregnancy: Endovascular Management With Fetal Preservation—A Case Report and Literature Review

Faisal Ahmed, Abdulqader Al‐falahi, Maeen Al‐Sayyadi, Bassam Al‐Ozair et al.
Clinical Case Reports
Tuberous Sclerosis Complex Research
article

Wunderlich Syndrome Caused by Spontaneous Rupture of Renal Angiomyolipoma in the Third Trimester of Pregnancy: Endovascular Management With Fetal Preservation—A Case Report and Literature Review

Faisal Ahmed, Abdulqader Al‐falahi, Maeen Al‐Sayyadi, Bassam Al‐Ozair, Ali Alwah
article en

Abstract

Renal angiomyolipoma (AML) are benign tumors incidentally diagnosed during routine radiologic images; nonetheless, AML rupture is uncommon and has been associated with fatal consequences, demanding prompt intervention, especially during pregnancy with symptoms of Wunderlich's syndrome (WS) and atrophied contralateral kidney. We report a 30-year-old pregnant woman who presented with gross hematuria and hypovolemic shock in her seventh month of pregnancy. Magnetic resonance imaging revealed a 15 × 13.5 × 16 cm AML mass in the left kidney, a 5 × 6 cm intrarenal pseudoaneurysm, and a massive retroperitoneal hematoma with an atrophied contralateral right kidney. After achieving hemodynamic stability, selective renal arterial embolization was performed with a successful outcome. She subsequently delivered her baby via cesarean section without complications. In conclusion, although WS due to AML rupture is rare during pregnancy, accurate diagnosis and prompt endovascular treatment should be pursued in cases involving a solitary kidney and associated comorbid conditions to safeguard the lives of both the patient and the baby, stabilize renal function, and prevent catastrophic complications.

Clinical Case ReportsVol. 13(2)
Sana'a University (YE), University of Modern Sciences (YE), 21 September University for Medical and Applied Sciences (YE), Ibb University (YE)
Good health and well-being
Openalex Percentile: Top 97%
Tuberous Sclerosis Complex Research
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