Urinary Estrogens in Girls Throughout Puberty as a Marker of Metabolic Risk and Their Relationship With Premature Adrenarche

Our investigation suggests that metabolic risk in patients without biochemical PA are mostly associated with estrone levels. In contrast, in patients with biochemical PA, androgens are associated with MetS. Therefore, metabolic disturbances throughout puberty might be generated by different pathways in girls with and without biochemical PA.

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Publication Details

Journal
Clinical Endocrinology
Published
2025-02-10
DOI
https://doi.org/10.1111/cen.15215
Primary Topic
Estrogen and related hormone effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Urinary Estrogens in Girls Throughout Puberty as a Marker of Metabolic Risk and Their Relationship With Premature Adrenarche

Diego Zepeda, Germán Íñiguez, Ana Pereira, Verónica Mericq
Clinical Endocrinology
Estrogen and related hormone effects
article

Urinary Estrogens in Girls Throughout Puberty as a Marker of Metabolic Risk and Their Relationship With Premature Adrenarche

Diego Zepeda, Germán Íñiguez, Ana Pereira, Verónica Mericq
article en

Abstract

Our investigation suggests that metabolic risk in patients without biochemical PA are mostly associated with estrone levels. In contrast, in patients with biochemical PA, androgens are associated with MetS. Therefore, metabolic disturbances throughout puberty might be generated by different pathways in girls with and without biochemical PA.

Clinical EndocrinologyVol. 102(6)
University of Chile (CL), University of Valparaíso (CL)
Good health and well-being
Openalex Percentile: Top 97%
Estrogen and related hormone effects
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