Capture of Totipotency in Mouse Embryonic Stem Cells in the Absence of <i>Pdzk1</i> (Adv. Sci. 6/2025)
Capture of totipotenCyIn article number 2408852, Ling Shuai, Qian Gao, Xiao-Ou Zhang, and co-workers report the generation of mouse totipotent-like stem cells through deletion of a single gene, Pdzk1.This novel and efficient strategy to acquire totipotency just like a beautiful genie has her powerful arrow to shoot the magic shining stars, representing the plasticity of development.
Authors
- Dan Ding (ORCID: https://orcid.org/0000-0001-9802-1894)
- Ling Shuai (ORCID: https://orcid.org/0000-0003-0671-7478)
- Xiao‐Ou Zhang (ORCID: https://orcid.org/0000-0002-2027-1313)
- Haisong Wang (ORCID: https://orcid.org/0000-0001-5601-2703)
- Chao Tong (ORCID: https://orcid.org/0000-0003-0828-2674)
- Qingshen Jia
- Yiding Zhao
- Qian Gao (ORCID: https://orcid.org/0000-0002-4425-9052)
- Wenhao Zhang (ORCID: https://orcid.org/0000-0003-2708-2221)
- Jing Yan (ORCID: https://orcid.org/0000-0003-1319-9453)
- Shaochen Nie
- Zhe Yang (ORCID: https://orcid.org/0000-0002-8674-6844)
Publication Details
- Journal
- Advanced Science
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/advs.202570035
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00