Review on Enhancing Predictive Accuracy in Alzheimer Detection: A Hybrid Approach

Effective early detection techniques are essential because to the tripled global prevalence of dementia, which is mostly caused by Alzheimer's disease (AD) and is predicted to reach 152 million by 2050. AD pathology, which has a preclinical phase lasting 10–20 years before severe cognitive impairment, is associated to about 70% of dementia cases. Early detection of AD is essential since medication trial success rates may be increased and risk factor management may avoid 40% of cases. Currently, lengthy cognitive tests that are insensitive to the pre-clinical stage are used to detect dementia. Initiatives to make open data available have gathered so much data on AD that it is now too much for humans to analyze. In order to diagnose AD accurately, machine learning (ML) has become essential, especially when it comes to early-stage AD prediction. AI and ML-driven healthcare research places a strong emphasis on automated disease prediction systems, including dementia detection. Finding those who is susceptible of ‘Alzheimer's disease’ (AD) progression is still difficult, especially in light of the disease's severity and fast advancement. Preventing the progression of the disease and planning the course of treatment depend on early detection. Reviewing AD detection research conducted since 2016 has highlighted the contribution of machine learning (ML) to improving prediction accuracy. The reviews provide information on participant demographics, data modalities, feature extraction strategies, and ML models used. By combining earlier studies, promoting critical analysis, and directing future investigations for early AD diagnosis, this thorough review helps researchers.