Evaluation of the Relationship between CD44 Expression and Gleason Grade among Prostate Adenocarcinoma and Benign Prostatic Hyperplasia: A Cross-Sectional Study

This study highlights CD44 expression not only as a potential biomarker for PAC diagnosis but also potential guide to therapeutic decision-making. Patients exhibiting lower CD44 levels may require closer monitoring and more aggressive treatment strategies, while those with higher expression may be candidates for less intensive management. Overall, our findings advocate for further investigation into CD44 as a biomarker for prostate cancer aggressiveness, which could ultimately enhance personalized treatment approaches and improve the patient outcomes.

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Institutions

Publication Details

Journal
Medical Principles and Practice
Published
2025-02-11
DOI
https://doi.org/10.1159/000544021
Citations
1
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
1.52

Funders

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article

Evaluation of the Relationship between CD44 Expression and Gleason Grade among Prostate Adenocarcinoma and Benign Prostatic Hyperplasia: A Cross-Sectional Study

Masood Soltanipur, Mohammadreza Jalali Nadoushan, Joben Kianparsa
1 citations
Medical Principles and Practice
Prostate Cancer Treatment and Research
1.52
article

Evaluation of the Relationship between CD44 Expression and Gleason Grade among Prostate Adenocarcinoma and Benign Prostatic Hyperplasia: A Cross-Sectional Study

Masood Soltanipur, Mohammadreza Jalali Nadoushan, Joben Kianparsa
article en
1 citations

Abstract

This study highlights CD44 expression not only as a potential biomarker for PAC diagnosis but also potential guide to therapeutic decision-making. Patients exhibiting lower CD44 levels may require closer monitoring and more aggressive treatment strategies, while those with higher expression may be candidates for less intensive management. Overall, our findings advocate for further investigation into CD44 as a biomarker for prostate cancer aggressiveness, which could ultimately enhance personalized treatment approaches and improve the patient outcomes.

Medical Principles and PracticeVol. 34(3)
Shahed University (IR), Academic Center for Education, Culture and Research (IR), Sina Hospital (IR), Motamed Cancer Institute (IR)
Shahed University
Openalex Percentile: Top 22%
Prostate Cancer Treatment and Research
1.52
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Evaluation of the Relationship between CD44 Expression and Gleason Grade among Prostate Adenocarcinoma and Benign Prostatic Hyperplasia: A Cross-Sectional Study — Masood Soltanipur, Mohammadreza Jalali Nadoushan, et al. · Medical Principles and Practice (2025) | TGRS Research Map | TGRS