Patient perspectives after receiving simulated preconception polygenic risk scores (PRS) for family planning
The findings examine the receipt of simulated embryo PRS in a patient population in which support for using PRS during embryo prioritization is high. Positive patient interest was consistent with other US studies; as prior studies identify significant clinician discomfort, these results highlight the need for comprehensive genetic counseling and inclusive stakeholder input in shaping guidelines for PRS during IVF.
Authors
- M. Katz (ORCID: https://orcid.org/0009-0008-2549-6387)
- Dhruva Chandramohan
- Noor Siddiqui
- Qinnan Zhang (ORCID: https://orcid.org/0000-0002-4608-4006)
- Barry Behr
- Yuntao Xia (ORCID: https://orcid.org/0000-0002-3011-5859)
- Benjamin Podgursky (ORCID: https://orcid.org/0009-0000-7072-4272)
- Funda Suer (ORCID: https://orcid.org/0000-0002-7790-6332)
Institutions
- Wolfspeed, Inc. (United States) (US)
- Orchid Pharma (India) (IN)
- Stanford University (US)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2025-02-11
- DOI
- https://doi.org/10.1007/s10815-025-03397-6
- Citations
- 4
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 7.27