Vitamin <scp>B12</scp> Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults
Healthy older subjects exhibit neurological changes at both ends of the measurable "normal" B12 spectrum. These findings challenge our current understanding of optimal serum B12 levels and suggest revisiting how we establish appropriate nutritional recommendations. ANN NEUROL 2025;97:1190-1204.
Authors
- Simone Sacco (ORCID: https://orcid.org/0000-0001-8789-3099)
- John Boscardin
- Shikha Saha (ORCID: https://orcid.org/0000-0002-5010-5105)
- Ari Green (ORCID: https://orcid.org/0000-0001-9275-3066)
- Adam M. Staffaroni (ORCID: https://orcid.org/0000-0002-3903-9805)
- Christian Cordano (ORCID: https://orcid.org/0000-0002-1413-0442)
- Azeen Keihani (ORCID: https://orcid.org/0000-0002-9040-6535)
- Kirtana Ananth
- Sree Gowrinadh Javvadi (ORCID: https://orcid.org/0000-0002-7967-0773)
- Martin J. Warren (ORCID: https://orcid.org/0000-0002-6028-6456)
- Ahmed Abdelhak (ORCID: https://orcid.org/0000-0001-9731-4169)
- Joshua W. Miller (ORCID: https://orcid.org/0000-0002-9126-0224)
- Rowan Saloner (ORCID: https://orcid.org/0000-0002-1351-6183)
- Christopher Songster
- Shivany Condor Montes (ORCID: https://orcid.org/0000-0003-1211-6046)
- Frederike Cosima Oertel (ORCID: https://orcid.org/0000-0003-4906-5983)
- Bruce Miller
- Ralph Green (ORCID: https://orcid.org/0000-0002-9935-230X)
- Apraham Gomez
- Alexandra Beaudry‐Richard (ORCID: https://orcid.org/0000-0002-5974-8916)
- Joel H. Kramer (ORCID: https://orcid.org/0000-0002-1206-404X)
- Makenna Chapman
- Nour Jabassini
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Ottawa (CA)
- University of California, San Francisco (US)
- Norwich Research Park (GB)
- University of California System (US)
- Quadram Institute (GB)
- Zero to Three (US)
- University of Genoa (IT)
- University of California, Davis (US)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1002/ana.27200
- Citations
- 13
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 20.02
Funders
- Fidelity Foundation