Effect of an intensive antiplaque regimen on microbiome outcomes after nonsurgical periodontal therapy
This study looked at how different treatments for gum disease change the bacteria in the gums of people with moderate to severe gum problems. Eighty-six people received standard gum treatments, and some also used a mouthwash and special tools to clean between their teeth at home. After 6 months, more people in the group that added the extra cleaning steps had healthier bacteria in their gums than people who received the standard treatment. However, not everyone responded the same way. The study found that the types of bacteria someone had at the start were better at predicting how well the treatment would work, more than the type of treatment itself. This means gum disease treatments may need to be personalized for better results.
Authors
- Robert J. Genco (ORCID: https://orcid.org/0000-0001-7604-506X)
- Karen L. Falkner (ORCID: https://orcid.org/0000-0003-2667-9472)
- Robert E. Schifferle (ORCID: https://orcid.org/0000-0002-5254-913X)
- Yoshiko Hayashi-Okada (ORCID: https://orcid.org/0000-0003-0475-0311)
- Keith L. Kirkwood (ORCID: https://orcid.org/0000-0003-4519-8973)
- Yasumitsu Shimizu
- Patricia I. Diaz (ORCID: https://orcid.org/0000-0002-9501-1145)
- Lu Li (ORCID: https://orcid.org/0000-0002-1145-6308)
- Joseph J. Zambon
Institutions
- Roswell Park Comprehensive Cancer Center (US)
- Sunstar (Japan) (JP)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- Journal of Periodontology
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1002/jper.24-0141
- Citations
- 2
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 2.93