Characterization of the effect of naltrexone/bupropion on body composition
NB-induced weight loss is associated with significant reductions in total percent fat mass, increase in total percent lean mass, and change in lean-to-fat mass ratio, in comparison to placebo. Larger studies are needed to further elucidate the clinical significance of these changes and impact of a potentially healthier metabolism.
Authors
- Vanessa Tardio (ORCID: https://orcid.org/0009-0003-7841-1619)
- Fernando Camacho (ORCID: https://orcid.org/0000-0001-8679-1912)
- Maxime Barakat (ORCID: https://orcid.org/0000-0002-3000-2125)
- Michael A. Tsoukas (ORCID: https://orcid.org/0000-0002-8326-7274)
- Peter Yin
Institutions
- McGill University Health Centre (CA)
- Bausch Health (Canada) (CA)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1111/dom.16235
- Citations
- 3
- Primary Topic
- Pharmacology and Obesity Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Orexigen Therapeutics
- Bausch Health
- Health Canada