Evaluating the Role of Gynecomastia Surgery in Improving Sexual Function and Hormonal Profiles

Abstract Background Patients with gynecomastia may experience hormonal imbalances and sexual dysfunctions, such as erectile and ejaculatory disorders. Objectives This study evaluates the changes in hormonal parameters and sexual function following gynecomastia surgery. Methods Thirty-two male patients (aged 15-65) without systemic or genetic comorbidities underwent gynecomastia surgery. Preoperative and postoperative hormonal parameters free and total testosterone, estrogen (EST), prolactin (PRL), follicle-stimulating hormone, luteinizing hormone, sex hormone–binding globulin, and sexual function scores (International Index of Erectile Function [IIEF], Premature Ejaculation Diagnostic Tool [PEDT]) were assessed. A urologist blinded to the study evaluated patients andrologically. Results The mean age of the patients was 25.69 ± 10.37 years. Postoperative PRL and EST levels significantly decreased (P = .03 and P < .001, respectively). All IIEF subscale scores showed significant postoperative improvements (P-values ranging from <.001 to .006). PEDT scores significantly decreased postoperatively (P < .001). Conclusions Surgical treatment of gynecomastia leads to significant improvements in hormonal parameters and sexual function. These benefits should be considered in surgical planning. Level of Evidence: 4