Urinary Levels of Neutrophil Gelatinase-associated Lipocalin and Cystatin C in Patients with Hepatitis B on Tenofovir Treatment
In this cross-sectional study, after controlling for confounding factors, we observed that TDF treatment was linked to elevated levels of urinary NGAL and cystatin C in 87 (38.4%) of the cases. Notably, increased levels of these biomarkers were also found in the younger age-group (18-35 years). These findings suggest the need for further prospective studies with larger sample sizes to better understand the direct impact of TDF on kidney function in hepatitis B patients.
Authors
- Himanshu Dandu (ORCID: https://orcid.org/0000-0001-5627-4412)
- Medhavi Gautam
- Ambuj Yadav (ORCID: https://orcid.org/0000-0003-1471-6539)
- Sumit Rungta (ORCID: https://orcid.org/0000-0003-3599-1388)
- Wahid Ali (ORCID: https://orcid.org/0000-0002-0474-6200)
- Amit Goel (ORCID: https://orcid.org/0000-0003-3525-9381)
- Virendra Atam
- Mahak Lamba (ORCID: https://orcid.org/0009-0008-9403-9331)
- Atin Singhai (ORCID: https://orcid.org/0000-0001-8018-0723)
- Shivani Rani
Institutions
- King George's Medical University (IN)
Publication Details
- Journal
- Journal of the Association of Physicians of India
- Published
- 2025-02-01
- DOI
- https://doi.org/10.59556/japi.73.0828
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00