Approach to Janus kinase inhibition for juvenile dermatomyositis among CARRA and PReS providers
Paediatric rheumatologists use JAKi off-label for refractory JDM. Most providers noted clinical improvement in their patients. Barriers to JAKi use include lack of clinical data and insurance coverage. Clinical trials are needed to provide better data on the efficacy and safety of JAKi.
Authors
- Bianca Lang (ORCID: https://orcid.org/0000-0002-5686-4276)
- Silvia Rosina (ORCID: https://orcid.org/0000-0002-3667-6155)
- Marc H.A. Jansen (ORCID: https://orcid.org/0000-0001-6969-8759)
- Belina Y. Yi (ORCID: https://orcid.org/0000-0003-2385-2591)
- Angela Hamilton
- Charalampia Papadopoulou (ORCID: https://orcid.org/0000-0002-1237-0557)
- Meredyth Wilkinson (ORCID: https://orcid.org/0000-0002-7972-8066)
- E. Datyner (ORCID: https://orcid.org/0009-0002-4231-182X)
- Brigitte Bader‐Meunier (ORCID: https://orcid.org/0000-0001-8476-8196)
- Raquel Campanilho‐Marques (ORCID: https://orcid.org/0000-0002-1894-8516)
- Saskia R Veldkamp (ORCID: https://orcid.org/0000-0002-1626-353X)
- Hanna Kim (ORCID: https://orcid.org/0000-0002-0595-6533)
- Helga Sanner (ORCID: https://orcid.org/0000-0001-7226-066X)
- Liza McCann (ORCID: https://orcid.org/0000-0002-0372-5758)
- Rebecca Nicolai (ORCID: https://orcid.org/0000-0003-4298-0628)
- Matthew A. Sherman (ORCID: https://orcid.org/0000-0002-5448-1538)
- Stacey E. Tarvin (ORCID: https://orcid.org/0000-0001-8583-7878)
- Susan Kim (ORCID: https://orcid.org/0000-0003-2159-8059)
- Kaveh Ardalan (ORCID: https://orcid.org/0000-0002-5552-4501)
- A. G. P. Brown
Institutions
- Oslo University Hospital (NO)
- Dalhousie University (CA)
- National Institutes of Health (US)
- Arkansas Children's Hospital (US)
- Johns Hopkins University (US)
- Duke University (US)
- University of California, San Francisco (US)
- OsloMet – Oslo Metropolitan University (NO)
- Johns Hopkins Medicine (US)
- Great Ormond Street Hospital (GB)
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- Istituto Giannina Gaslini (IT)
- University Medical Center Utrecht (NL)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
- Alder Hey Children's NHS Foundation Trust (GB)
- Assistance Publique – Hôpitaux de Paris (FR)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- Arthritis UK (GB)
- Bambino Gesù Children's Hospital (IT)
- National Institute of Allergy and Infectious Diseases (US)
- ERN GUARD-Heart (NL)
- Hospital de Santa Maria (PT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Wilhelmina Children's Hospital (NL)
- Indiana University School of Medicine
- University College London (GB)
- Indiana University – Purdue University Indianapolis (US)
- University of Arkansas for Medical Sciences (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1093/rheumatology/keaf086
- Citations
- 1
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Childhood Arthritis and Rheumatology Research Alliance
- National Institutes of Health