Clinical and metabolic profiles in behavioural frontotemporal dementia: Impact of age at onset
The cognitive-behavioural profile of bvFTD differs between early- and late-onset, already from the prodromal stage of the disease. Both metabolic pattern and functional connectivity vary based on age-at-onset. Understanding these differences could contribute to improve diagnostic accuracy and understanding the underling pathological heterogeneity.
Authors
- Stefano Caneva (ORCID: https://orcid.org/0000-0002-4064-6936)
- Stefano Raffa
- Luca Roccatagliata (ORCID: https://orcid.org/0000-0001-8029-3947)
- Francesco Calizzano
- Gianmario Sambuceti (ORCID: https://orcid.org/0000-0003-2979-6500)
- Sara Garbarino (ORCID: https://orcid.org/0000-0002-3583-3630)
- Paola Mandich (ORCID: https://orcid.org/0000-0003-3123-3512)
- Matteo Bauckneht (ORCID: https://orcid.org/0000-0002-1937-9116)
- Antonio Uccelli (ORCID: https://orcid.org/0000-0002-2008-6038)
- Pietro Mattioli (ORCID: https://orcid.org/0000-0003-2563-5830)
- Giulia Bozzo
- Andrea Brugnolo (ORCID: https://orcid.org/0000-0002-5708-0940)
- Nicola Girtler (ORCID: https://orcid.org/0000-0001-8119-8642)
- Federico Massa (ORCID: https://orcid.org/0000-0001-5667-204X)
- Paola Origone
- Matteo Pardini (ORCID: https://orcid.org/0000-0002-4740-1982)
- Gianluca Serafini (ORCID: https://orcid.org/0000-0002-6631-856X)
- Fabio Gotta
- Dario Arnaldi (ORCID: https://orcid.org/0000-0001-6823-6069)
- A. Cirone (ORCID: https://orcid.org/0000-0003-4299-8609)
- Silvia Daniela Morbelli (ORCID: https://orcid.org/0000-0002-7833-6095)
- Beatrice Orso (ORCID: https://orcid.org/0000-0001-9983-7940)
- Michele Piana (ORCID: https://orcid.org/0000-0003-1700-991X)
- Lucia Argenti (ORCID: https://orcid.org/0009-0008-7444-1411)
- Mattia Losa (ORCID: https://orcid.org/0009-0008-2942-1307)
- Antonio Canosa
- Lorenzo Lombardo (ORCID: https://orcid.org/0009-0009-4251-0512)
Institutions
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Department of Medical Sciences (RU)
- Ospedale Policlinico San Martino (IT)
- University of Turin (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Cortex
- Published
- 2025-02-11
- DOI
- https://doi.org/10.1016/j.cortex.2025.01.011
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Ministero dell’Istruzione, dell’Università e della Ricerca