Cerebral Sinovenous Thrombosis in Neonates: A Report of Three Cases

The clinical aspects of neonatal cerebral sinovenous thrombosis (CSVT) are polymorphic in their onset and acute phase, making diagnosis challenging. The aim of our study is to shed light on this pathology through three clinical cases. This is a case series study of three cases of CSVT in newborns collected in the neonatology and neonatal intensive care unit at CHU Mohammed VI Oujda over a one-year period. The first patient was a male with a neonatal infection of indeterminate origin. He presented with convulsions, and a cerebral MRI revealed CSVT of the superior longitudinal sinus. The permeabilization of the venous sinus marked the course. The other two patients presented with CSVT, complicating bacterial meningitis. One of them, whose thrombosis had spread to multiple sinuses and was associated with ventriculitis, had a poor prognosis with thrombus extension and was scheduled for surgery. The second patient, whose thrombosis was confined to the superior longitudinal sinus, had a favorable outcome with complete repermeabilization of the sinus.