The role of genetic polymorphisms in folate metabolism genes in the manifestation of migraine in children
Patients with migraine showed a higher prevalence of the rare homozygous 677TT genotype of the <i>MTHFR</i> gene, which leads to elevated plasma homocysteine levels, often associated with latent folate deficiency. The use of «Cortexin» significantly improved the patients' condition, reducing complaints of headaches, fatigue, and emotional instability.
Authors
- Viktor S. Ponomarev (ORCID: https://orcid.org/0000-0002-7794-8129)
- Lyudmila A. Strozenko (ORCID: https://orcid.org/0000-0002-8586-1330)
- Yu.F. Lobanov (ORCID: https://orcid.org/0000-0001-6284-1604)
- Olga O. Sanina (ORCID: https://orcid.org/0009-0008-0370-371X)
Institutions
- Altai State Medical University (RU)
- City Children's Hospital No. 22 (RU)
Publication Details
- Journal
- S S Korsakov Journal of Neurology and Psychiatry
- Published
- 2025-02-11
- DOI
- https://doi.org/10.17116/jnevro202512501147
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00