The association of NOS1AP gene polymorphisms with the duration of the QT interval in patients with schizophrenia receiving antipsychotic therapy
Genetic variants rs12029454, rs10494366 and rs12143842 of the <i>NOS1AP</i> gene are associated with the duration of the QTc interval in men with schizophrenia in response to antipsychotics. The <i>AA</i>/<i>AG</i> rs12029454, <i>GG</i>/<i>GT</i> rs10494366 and <i>TT</i>/<i>CT</i> rs12143842 genotypes in men contribute to the prolongation of the QTc interval and the development of undesirable cardiovascular disorders against the background of antipsychotic therapy.
Authors
- S. А. Galkin (ORCID: https://orcid.org/0000-0002-7709-3917)
- Elena G. Kornetova (ORCID: https://orcid.org/0000-0002-5179-9727)
- Irina A. Mednova (ORCID: https://orcid.org/0000-0002-8057-3305)
- V. V. Tiguntsev (ORCID: https://orcid.org/0000-0001-9083-0339)
- Svetlana А. Ivanova (ORCID: https://orcid.org/0000-0001-7078-323X)
- Diana Z. Paderina (ORCID: https://orcid.org/0000-0002-5546-7316)
Institutions
- Mental Health Research Institute (AU)
- Tomsk National Research Medical Center (RU)
Publication Details
- Journal
- S S Korsakov Journal of Neurology and Psychiatry
- Published
- 2025-02-11
- DOI
- https://doi.org/10.17116/jnevro202512501198
- Citations
- 1
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 1.39