Evaluation of the analytical performance of a point‐of‐care analyzer for the measurement of feline serum thyroxine concentration in comparison with a chemiluminescence enzyme immunoassay

The analytical performance of the POCA was excellent, as was its correlation with the reference method. Except for the interferent effect of hemoglobin, the TE<sub>obs</sub> was <TE<sub>a</sub> for all analyses. Analysis of severely hemolytic samples is not advised. However, the relatively small dynamic range of the POCA precludes quantitative analysis of samples with TT4 >8 μg/dL, and de novo reference intervals need to be established.

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Publication Details

Journal
Veterinary Clinical Pathology
Published
2025-02-10
DOI
https://doi.org/10.1111/vcp.13416
Primary Topic
Blood groups and transfusion
Type
article
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article

Evaluation of the analytical performance of a point‐of‐care analyzer for the measurement of feline serum thyroxine concentration in comparison with a chemiluminescence enzyme immunoassay

Natali Bauer, Kristina Weiler, Agnes C. Gläsel, Alexander Pankraz
Veterinary Clinical Pathology
Blood groups and transfusion
article

Evaluation of the analytical performance of a point‐of‐care analyzer for the measurement of feline serum thyroxine concentration in comparison with a chemiluminescence enzyme immunoassay

Natali Bauer, Kristina Weiler, Agnes C. Gläsel, Alexander Pankraz
article en

Abstract

The analytical performance of the POCA was excellent, as was its correlation with the reference method. Except for the interferent effect of hemoglobin, the TE<sub>obs</sub> was <TE<sub>a</sub> for all analyses. Analysis of severely hemolytic samples is not advised. However, the relatively small dynamic range of the POCA precludes quantitative analysis of samples with TT4 >8 μg/dL, and de novo reference intervals need to be established.

Veterinary Clinical PathologyVol. 54(1)
Justus-Liebig-Universität Gießen (DE)
Openalex Percentile: Top 97%
Blood groups and transfusion
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