THE INFLUENCE OF SEASONAL FACTORS ON LEUKOCYTE FORMULA INDICATORS IN STUDENTS DURING MARTIAL LAW

The influence of seasonal factors (autumn and spring) on the leukocyte formula of students during the period of martial law was analyzed. A shift to the lower limit of the norm of lymphocyte indicators and to the upper limit of neutrophil indicators in the autumn period was revealed, which indicates chronic stress caused by martial law and the formation of an adaptive response. In the spring, there is an overstrain of the lymphocyte link and an imbalance in the indicators of the nonspecific link of cellular immunity at the level of monocytes, neutrophils and basophils. The reasons for such an imbalance can be considered the initial chronic stress in the autumn period, increased antigenic load in the winter period, caused by the circulation of SARS-CoV2 and other pathogens of acute respiratory diseases and, as a result, the depletion of adaptive resources of cellular immunity.