The association between serum lipids at diagnosis and renal outcome in microscopic polyangiitis patients
In MPA patients, high TG or VLDL at diagnosis is associated with an increased risk of ESRD development. The potential mechanisms may be associated with the upregulation of profibrotic and inflammatory signaling pathways, and the activation of complement and coagulation cascades.
Authors
- Jingzhi Xie
- Zhimin Chen (ORCID: https://orcid.org/0000-0002-4260-1774)
- Yanfang Xu (ORCID: https://orcid.org/0000-0002-6207-545X)
- Yujia Wang (ORCID: https://orcid.org/0000-0001-8434-4801)
- Zigui Zheng
- Bingjing Jiang
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-02-10
- DOI
- https://doi.org/10.7717/peerj.18839
- Citations
- 1
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China
- Fujian Provincial Health Commission