Analytical and clinical validation of a novel MeltPlus TB-NTM/RIF platform for simultaneous detection of Mycobacterium tuberculosis complex, Non-Tuberculous Mycobacteria and rifampicin resistance
These findings indicate that the novel MeltPlus MTB-NTM/RIF platform provides a rapid and accurate method for the simultaneously detecting MTBC, NTM, and RIF resistance, making it a promising tool for clinical TB/NTM diagnosis and management, further multi-center and field studies are recommended to validate its broader applicability.
Authors
- Guanghong Bai
- Zhuo Wang (ORCID: https://orcid.org/0000-0002-8218-6819)
- Zhenbo Wei (ORCID: https://orcid.org/0000-0002-4603-1422)
- Yaping Jiang (ORCID: https://orcid.org/0000-0003-3370-0348)
- Xiaolin Wang (ORCID: https://orcid.org/0000-0001-7578-7379)
- Jie Shi (ORCID: https://orcid.org/0000-0001-8921-9559)
- Yuanwu Zou
- Shaoyi Qu
- Cuijiao Gu
Institutions
- Shanxi Medical University (CN)
- Northwest University (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-02-10
- DOI
- https://doi.org/10.3389/fcimb.2025.1534268
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00