Case report: From misdiagnosis to timely detection: a clinical and imaging guide to neurological presentations of diffuse large B-cell lymphoma—insights from six cases

The differential diagnostic process for the misdiagnosed conditions in these cases has been meticulously revisited, enhancing the diagnostic acumen of neurologists. These cases underscore the imperative for neurologists to maintain a high index of suspicion for lymphoma in atypical presentations and to judiciously integrate multimodal diagnostic modalities-such as comprehensive imaging, cerebrospinal fluid analysis, and biopsy-to expedite diagnosis and initiate timely intervention.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-02-10
DOI
https://doi.org/10.3389/fonc.2025.1410953
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Case report: From misdiagnosis to timely detection: a clinical and imaging guide to neurological presentations of diffuse large B-cell lymphoma—insights from six cases

W. Na, Zihua Gong, Shengyuan Yu, Huijuan Yuan et al.
Frontiers in Oncology
CNS Lymphoma Diagnosis and Treatment
article

Case report: From misdiagnosis to timely detection: a clinical and imaging guide to neurological presentations of diffuse large B-cell lymphoma—insights from six cases

W. Na, Zihua Gong, Shengyuan Yu, Huijuan Yuan, Wei Xie, Tao Wang, Chunxiao Yang
article en

Abstract

The differential diagnostic process for the misdiagnosed conditions in these cases has been meticulously revisited, enhancing the diagnostic acumen of neurologists. These cases underscore the imperative for neurologists to maintain a high index of suspicion for lymphoma in atypical presentations and to judiciously integrate multimodal diagnostic modalities-such as comprehensive imaging, cerebrospinal fluid analysis, and biopsy-to expedite diagnosis and initiate timely intervention.

Frontiers in OncologyVol. 15
Nankai University (CN), Chinese PLA General Hospital (CN), Bethune International Peace Hospital (CN), Chinese People's Liberation Army (CN)
General Hospital of People’s Liberation Army
Good health and well-being
Openalex Percentile: Top 96%
CNS Lymphoma Diagnosis and Treatment
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