iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis
The iPSC-Exo/AmB complex is a promising therapeutic strategy that enhances AmB efficacy while reducing toxicity, offering new hope for treating CM and other refractory fungal infections of the central nervous system.
Authors
- Jingyu Zhao (ORCID: https://orcid.org/0009-0008-9786-4847)
- Jiquan Chen (ORCID: https://orcid.org/0000-0003-0761-9458)
- Julin Gu
- Guizhen Wang (ORCID: https://orcid.org/0000-0002-7333-6803)
- Wei Fang
- Yangjie Gao
Institutions
- Tongji University (CN)
- Shanghai Jiao Tong University (CN)
- Soochow University (CN)
- Shanghai Ninth People's Hospital (CN)
- Shanghai Tenth People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-02-10
- DOI
- https://doi.org/10.3389/fmicb.2025.1531425
- Citations
- 5
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- National Natural Science Foundation of China