Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach
The present study revealed that SSA exerts anti-tumorigenic effects in prostate cancer by targeting multiple pathways, laying a theoretical reference for its use as a therapeutic candidate for prostate cancer.
Authors
- Xuannian Wang (ORCID: https://orcid.org/0009-0009-6948-2494)
- Kemeng Tan
- Zhiming Jiang (ORCID: https://orcid.org/0000-0003-3117-6263)
- Heng Tang (ORCID: https://orcid.org/0000-0003-0959-3650)
- Yiqing Meng
- Genbao Zhu (ORCID: https://orcid.org/0000-0002-4312-7832)
- Ningfeng Zhu (ORCID: https://orcid.org/0000-0002-3037-2003)
- Donghui Wang (ORCID: https://orcid.org/0000-0002-4401-6886)
- Tianqi Guo (ORCID: https://orcid.org/0000-0003-0193-1598)
- Yi Zhu (ORCID: https://orcid.org/0000-0002-9640-3183)
- Mengxue Hu
Institutions
- China Coal Technology and Engineering Group Corp (China) (CN)
- Henan Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-10
- DOI
- https://doi.org/10.3389/fphar.2025.1530715
- Citations
- 5
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 4.03