Inositol – multidimensional support for metabolic and mental health

Inositol, a naturally occurring compound from the glucose family, is crucial in maintaining metabolic and mental health.The two most physiologically active isomers, myo-inositol (MI) and D-chiro-inositol (DCI), are involved in important cellular processes such as insulin signaling, lipid metabolism, and neurotransmitter modulation.This article explores the various aspects of inositol, including its physiological processes, nutritional sources, and medicinal uses.Inositol is showing promise in treating conditions including insulin resistance, type 2 diabetes, polycystic ovary syndrome (PCOS), and mood disorders such as depression, panic disorder, and obsessive-compulsive disorder (OCD).With a favorable safety profile, this natural origin makes it an attractive alternative or adjunctive therapy for metabolic and mental health conditions.Further work is necessary to optimize supplementation strategies, address uncertainties regarding mechanisms of action, and assess long-term benefits in other populations.

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Publication Details

Journal
Medical Science
Published
2025-02-07
DOI
https://doi.org/10.54905/disssi.v29i156.e23ms3530
Citations
1
Primary Topic
Diet, Metabolism, and Disease
Type
article
Field-Weighted Citation Impact
1.29
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Inositol – multidimensional support for metabolic and mental health

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article en
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Abstract

Inositol, a naturally occurring compound from the glucose family, is crucial in maintaining metabolic and mental health.The two most physiologically active isomers, myo-inositol (MI) and D-chiro-inositol (DCI), are involved in important cellular processes such as insulin signaling, lipid metabolism, and neurotransmitter modulation.This article explores the various aspects of inositol, including its physiological processes, nutritional sources, and medicinal uses.Inositol is showing promise in treating conditions including insulin resistance, type 2 diabetes, polycystic ovary syndrome (PCOS), and mood disorders such as depression, panic disorder, and obsessive-compulsive disorder (OCD).With a favorable safety profile, this natural origin makes it an attractive alternative or adjunctive therapy for metabolic and mental health conditions.Further work is necessary to optimize supplementation strategies, address uncertainties regarding mechanisms of action, and assess long-term benefits in other populations.

Medical ScienceVol. 29(156)
Openalex Percentile: Top 23%
Diet, Metabolism, and Disease
1.29
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