Study on the mechanical properties of biomolecules in watershed water resource management

This study focuses on the mechanical properties of biomolecules and their interactions within the extracellular matrix in the context of watershed water resource management. We utilized a modified WEAP-MODFLOW model to explore how these interactions influence the allocation and management of water resources. The WEAP model serves as a comprehensive tool for assessing the balance of surface water supply and demand, while the MODFLOW model is employed for simulating deep groundwater flow. By integrating these models, we can examine the mechanical behavior of biomolecules and cells in response to varying hydrological conditions, thus enhancing our understanding of their role in water resource dynamics. To improve model accuracy, parameters were calibrated using observed flow data from relevant biological systems. Key evaluation metrics, including the coefficient of determination, Nash efficiency coefficient, and deviation coefficient, were employed to assess simulation accuracy. On a monthly scale, the coefficient of determination reached 0.98, indicating a strong correlation between simulated and observed values. The Nash efficiency coefficient was 0.97, reflecting high accuracy in simulating flow dynamics. Furthermore, a deviation coefficient of −12% suggests minimal systematic bias in the simulation results. During the validation phase, these metrics maintained high accuracy, with a determination coefficient of 0.97, a Nash efficiency coefficient of 0.97, and a deviation coefficient of −3.30%. These findings highlight the reliability of the improved WEAP-MODFLOW model in simulating the mechanical properties of biomolecules and their interactions with water resources, ultimately contributing to optimized water resource management strategies.