Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report
In the previous guideline recommendations, patients who have had a stroke within 3 months are excluded from intravenous thrombolysis (IVT) regimens. Some studies have suggested that IVT with alteplase (rt-PA) may be effective and safe in such patients, but evidence supporting the use of tenecteplase (TNK) is not sufficient. This paper includes an 80-year-old male patient readmitted for recurrence of ischaemic stroke (IS) after 48 days, who received TNK IVT as a bridging therapy prior to thrombectomy, with favourable results at 8-week follow-up. This case highlights that TNK alone or IVT as a bridging therapy prior to thrombectomy can also benefit patients with recurrent stroke within 3 months.
Authors
- Yuzhu Xu (ORCID: https://orcid.org/0009-0005-5839-297X)
- Junyan Liu (ORCID: https://orcid.org/0000-0002-8331-5117)
- Cuicui Liu (ORCID: https://orcid.org/0000-0003-1592-9384)
- Huiling Ren (ORCID: https://orcid.org/0000-0002-6043-1414)
- W. Liu (ORCID: https://orcid.org/0009-0002-5596-2998)
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- International Medical Case Reports Journal
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/imcrj.s497458
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00