Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report

In the previous guideline recommendations, patients who have had a stroke within 3 months are excluded from intravenous thrombolysis (IVT) regimens. Some studies have suggested that IVT with alteplase (rt-PA) may be effective and safe in such patients, but evidence supporting the use of tenecteplase (TNK) is not sufficient. This paper includes an 80-year-old male patient readmitted for recurrence of ischaemic stroke (IS) after 48 days, who received TNK IVT as a bridging therapy prior to thrombectomy, with favourable results at 8-week follow-up. This case highlights that TNK alone or IVT as a bridging therapy prior to thrombectomy can also benefit patients with recurrent stroke within 3 months.

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Publication Details

Journal
International Medical Case Reports Journal
Published
2025-02-01
DOI
https://doi.org/10.2147/imcrj.s497458
Primary Topic
Acute Ischemic Stroke Management
Type
article
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article

Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report

Yuzhu Xu, Junyan Liu, Cuicui Liu, Huiling Ren et al.
International Medical Case Reports Journal
Acute Ischemic Stroke Management
article

Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report

Yuzhu Xu, Junyan Liu, Cuicui Liu, Huiling Ren, W. Liu
article en

Abstract

In the previous guideline recommendations, patients who have had a stroke within 3 months are excluded from intravenous thrombolysis (IVT) regimens. Some studies have suggested that IVT with alteplase (rt-PA) may be effective and safe in such patients, but evidence supporting the use of tenecteplase (TNK) is not sufficient. This paper includes an 80-year-old male patient readmitted for recurrence of ischaemic stroke (IS) after 48 days, who received TNK IVT as a bridging therapy prior to thrombectomy, with favourable results at 8-week follow-up. This case highlights that TNK alone or IVT as a bridging therapy prior to thrombectomy can also benefit patients with recurrent stroke within 3 months.

International Medical Case Reports JournalVol. Volume 18
Hebei Medical University (CN), Third Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 96%
Acute Ischemic Stroke Management
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