Pituitary extramedullary plasmacytoma without any systemic involvement: a rare case report

Extramedullary plasmacytoma (EMP) is a rare plasma cell disorder of the soft tissue without systemic involvement like multiple myeloma (MM). It develops outside of the bone marrow. It happens seldom for a plasma cell neoplasm to manifest as an intracranial or cranial tumor, and it is much less common for it to resemble a pituitary adenoma. In patients with sellar area plasmacytomas, headaches, cranial nerve deficits, visual abnormalities, bloody nasal discharge, and discomfort in the eyes and craniofacial regions are common presentations. A biopsy is required to make the diagnosis. For parasellar plasmacytomas to be successfully managed, an accurate diagnosis is essential. Overall, patient survival is very good, although it might be lowered if they go on to develop overt MM. If there is no known history of MM, it is advised to do a thorough workup to identify any underlying MM or to closely monitor any MM development in the future. In this study, we aimed to report a rare case who presented with loss of vision without systemic involvement of MM and whose pituitary biopsy was a plasmacytoma.

Authors

Publication Details

Journal
Journal of Current Hematology & Oncology Research
Published
2025-02-04
DOI
https://doi.org/10.51271/jchor-0054
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Pituitary extramedullary plasmacytoma without any systemic involvement: a rare case report

Pınar Karabağli, Hakan Karabağlı, Mert Şahinoğlu, Rafiye Çiftçiler
Journal of Current Hematology & Oncology Research
Multiple Myeloma Research and Treatments
article

Pituitary extramedullary plasmacytoma without any systemic involvement: a rare case report

Pınar Karabağli, Hakan Karabağlı, Mert Şahinoğlu, Rafiye Çiftçiler
article en

Abstract

Extramedullary plasmacytoma (EMP) is a rare plasma cell disorder of the soft tissue without systemic involvement like multiple myeloma (MM). It develops outside of the bone marrow. It happens seldom for a plasma cell neoplasm to manifest as an intracranial or cranial tumor, and it is much less common for it to resemble a pituitary adenoma. In patients with sellar area plasmacytomas, headaches, cranial nerve deficits, visual abnormalities, bloody nasal discharge, and discomfort in the eyes and craniofacial regions are common presentations. A biopsy is required to make the diagnosis. For parasellar plasmacytomas to be successfully managed, an accurate diagnosis is essential. Overall, patient survival is very good, although it might be lowered if they go on to develop overt MM. If there is no known history of MM, it is advised to do a thorough workup to identify any underlying MM or to closely monitor any MM development in the future. In this study, we aimed to report a rare case who presented with loss of vision without systemic involvement of MM and whose pituitary biopsy was a plasmacytoma.

Journal of Current Hematology & Oncology ResearchVol. 3(1)
Openalex Percentile: Top 97%
Multiple Myeloma Research and Treatments
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